This study aims to determine whether ventral striatal dopamine release is a mechanism of
reward motivation in major depression, whether dopamine release is low in depression, and
whether DA release and reward motivation predict response to dopamine-targeted treatment with
pramipexole.
Phase:
Phase 4
Details
Lead Sponsor:
New York State Psychiatric Institute
Collaborators:
Columbia University Icahn School of Medicine at Mount Sinai Mclean Hospital National Institute of Mental Health (NIMH) Research Foundation for Mental Hygiene, Inc.