Iloprost Effects on Gas Exchange and Pulmonary Mechanics
Status:
Completed
Trial end date:
2012-07-01
Target enrollment:
Participant gender:
Summary
This study will examine the hypothesis that iloprost maintains and improves ventilation
perfusion matching in patients with pulmonary hypertension and ARDS/ALI as reflected by 1) an
improved PaO2/FIO2 ratio as calculated from the measured arterial blood gases obtained before
and after iloprost administration, 2) an improvement in lung compliance, and 3) an
improvement in the ventilatory equivalents for oxygen and CO2 measured by expired gas
analysis.