Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes
Status:
Completed
Trial end date:
2019-12-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate how the brain responds to low blood glucose in
non-diabetic individuals. The ultimate goal is to understand the brain substrates of
hypoglycemia unawareness, a condition that can occur in patients with type1 diabetes
undergoing insulin treatment.In the present study, the investigators focus on differences
between two groups of non-diabetic subjects: one group who experienced two episodes of
hypoglycemia the day prior to the study (and supposedly developed some level of unawareness
to hypoglycemia), and one group who did not. In this study, a 3 tesla MRI scanner is used to
acquire brain images. The imaging system is identical to the ones used in hospitals.
Phase:
Early Phase 1
Details
Lead Sponsor:
University of Minnesota University of Minnesota - Clinical and Translational Science Institute