Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach
Status:
Recruiting
Trial end date:
2028-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this research is to determine whether there is more extensive inflammation in
the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood
disorder, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The
research will also explore whether there is more inflammation in patients with more
neuropsychiatric symptoms. Inflammation in the brain will identified by using Positron
Emission Tomography (PET) with the radiotracer [11C]PBR-28 or [11C]ER176.
Phase:
Phase 1
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston