Overview

Identification of Neuropsychological, Genetic and Neuroimaging Markers and Treatment Response Predictors of ADHD

Status:
Unknown status
Trial end date:
2020-12-31
Target enrollment:
0
Participant gender:
All
Summary
The objective of this study is to identification of neuropsychological, genetic and neuroimaging markers and treatment response predictors of attention-deficit/hyperactivity disorder (ADHD). Participants who take the standardized pharmacotherapy (methylphenidate or atomoxetine) for ADHD will be observed for 52 weeks. They will do several neuropsychological, neuroimaging and genetic tests at visit 1~6.
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Asan Medical Center
Treatments:
Atomoxetine Hydrochloride
Methylphenidate
Criteria
Inclusion Criteria:

1. aged between 6 and 12 years

2. met the Diagnostic and Statistical Manual IV Text Revision (DSM-IV-TR) diagnostic
criteria for ADHD and needed pharmacotherapy.

3. Informed consent

Exclusion Criteria:

1. presence of intellectual disability or learning disorder

2. past and/or current history of bipolar disorder or psychosis or substance use disorder

3. past and/or current history of pervasive developmental disorder, organic mental
disorder or other neurological disorder

4. presence of sever suicidal ideation

5. presence of tic disorder or obsessive-compulsive disorder whose symptoms needed
pharmacotherapy

6. presence of family history with Tourette's Syndrome

7. took medication with methylphenidate or atomoxetine with last 6 month (or more than 3
month)

8. presence of severe medical condition (ex. cardiologic, liver, kidney, pulmonary,
glaucoma)

9. took alpha 2 adrenergic receptor agonist, antidepressant, antipsychotics,
benzodiazepine, modafinil, antiepileptic drug or dietary supplement that have a
influence on Central Nervous System (CNS).

10. presence of possibility with pregnancy

11. especially for neuroimaging,

1. uncooperative with claustrophobia or body movement

2. metal material inside body that can't take off