Ibuprofen Versus Ibuprofen/Acetaminophen Postoperatively in Patients Needing Root Canal Therapy

• Status: Completed
• Trial end date: 2017-07-17
• Target enrollment: 0
• Participant gender: All

Summary

Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting.

Methodology: Following regular root canal treatment, patients randomly received identical appearing tablets of 600 mg ibuprofen or 600 mg ibuprofen/650 mg acetaminophen to be taken every 6 hours as needed for pain. A 4-day diary was used to record pain and medication use.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ohio State University
• Treatments: Acetaminophen; Ibuprofen

Criteria

Inclusion Criteria:

1. mandibular (bottom) or maxillary (top) posterior (back) tooth requiring root canal treatment

2. mandibular (bottom) or maxillary (top) posterior (back) tooth with symptomatic irreversible pulpitis and symptomatic apical periodontitis (painful tooth to cold and biting)

2. between the ages of 18 and 65 years of age 3. American Society of Anesthesiologist classification I

Exclusion Criteria:

1. patients younger than 18 or older than 65 years of age

2. American Society of Anesthesiologist classification II or higher

3. allergies or contraindications to ibuprofen

4. allergies or contraindications to acetaminophen

5. pregnancy

6. inability to give informed consent