Overview

IVIG and Rituximab in Antibody-associated Psychosis - SINAPPS2

Status:
Recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
A randomised phase II double-blinded placebo-controlled trial designed to explore the utility of immunotherapy for patients with acute psychosis associated with anti-neuronal membranes (NMDA-receptor or Voltage Gated Potassium Channel). Primary objective: To test the efficacy of immunotherapy (IVIG and rituximab) for patients with acute psychosis associated with anti-neuronal membranes. Secondary objective: To test safety of immunotherapy (IVIG and rituximab) for patients with acute psychosis associated with anti-neuronal membranes.
Phase:
Phase 2
Details
Lead Sponsor:
University of Cambridge
Collaborator:
University of Oxford
Treatments:
Antibodies
gamma-Globulins
Immunoglobulins
Immunoglobulins, Intravenous
Rho(D) Immune Globulin
Rituximab