IV Ketorolac on Platelet Function Post-Cesarean Delivery
Status:
Recruiting
Trial end date:
2022-01-01
Target enrollment:
Participant gender:
Summary
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal
anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean
analgesia and markedly reduce opioid consumption. The effect of NSAIDs on healthy volunteers
results in inhibition of platelet aggregation and prolonged bleeding time. However, in the
obstetric population, the presence and degree of platelet inhibition after NSAID exposure is
less clear. The investigators plan to use Platelet Aggregometry and Thromboelastography (TEG)
to evaluate the effect of ketorolac on platelets.