IPACK Block in Total Knee Arthroplasty

• Status: Unknown status
• Trial end date: 2020-07-01
• Target enrollment: 0
• Participant gender: All

Summary

100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed preoperatively and group B (n=50) where an adductor canal block only will be performed preoperatively. All patients will receive a standardized multimodal approach, including pregabalin, paracetamol, and PCA with morphine. NRS scores in static and dynamic conditions during the first 48 hours postoperatively, morphine consumption during the first 24 hours postoperatively will be measured and additionally, patient satisfaction, complications, range of knee motion, moblization, functionality, delirium ocurence will be recorded. Chronic pain will be assessed in 3 and 6 months postoperatively.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Asklepieion Voulas General Hospital
• Collaborators: Aikaterini Kalampokini; Chryssoula Staikou

Criteria

Inclusion Criteria:

• Physical status according to American Society of Anesthesiologists (ASA) I-III

• Patients scheduled for total knee arthroplasty

Exclusion Criteria:

• Previous operation on same knee

• Contraindication of spinal anesthesia, peripheral nerve blocks or any of the agents used in the protocol

• BMI above 32

• Serious psychiatric, mental and cognitive disorders

• Language barrier

• Block failure

• Chronic opioid, gabapentinoid use

• Severe kidney disfunction