INVEST: INternational VErapamil SR Trandolapril STudy
Status:
Completed
Trial end date:
2003-02-01
Target enrollment:
Participant gender:
Summary
Because blood pressure affects the heart, blood vessels, kidneys, and the entire body, it is
important to keep it as normal as possible. There are several different ways to control blood
pressure and to prevent or limit the development of heart disease due to high blood pressure.
The purpose of this study is to compare two treatments to see how well they work and the
difference in their side effects. One treatment includes the use of a calcium antagonist drug
(Isoptin sustained release [SR] or Verapamil SR). The other treatment excludes the calcium
antagonist and may include a non-calcium antagonist drug called a beta blocker (Tenormin or
Atenolol). Both treatments may also include medication called angiotensin converting enzyme
(ACE) inhibitors and water pills. None of the drugs in this study are experimental, they are
all approved by the Food and Drug Administration (FDA).