IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease
Status:
RECRUITING
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
This is a single center, open-label, prospective, investigation to quantify the effects liver congestion and fibrosis has on hepatic drug metabolism and transport in children, adolescents, and young adults with Fontan circulation.
Phase:
PHASE1
Details
Lead Sponsor:
Children's Mercy Hospital Kansas City
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Indiana Clinical and Translational Sciences Institute
Treatments:
Glycation End Products, Advanced Pravastatin Sildenafil Citrate Tablets