IIaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients
Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the efficacy and safety of ilaprazole and omeprazole
in the treatment and prevention of peptic ulcer bleeding. Patients with endoscopically
diagnosed peptic ulcer bleeding were enrolled in a randomized, double-blind, parallel and
positive-controlled trial. They were randomly assigned into two groups, ilaprazole and
omeprazole, to be treated for up to 30 days and be seen at day 3, 4, 7, 14 and 30. The
primary endpoint was the hemostasis rate (hemostatic groups with endoscopy check ) and
re-bleeding rate ( bleeding groups with endoscopy check) within 72 hours. Secondary end
points include effective rate of hemostasis, mean volume of blood transfusion, the length of
stay and re-bleeding rate, etc.