IINB vs. QLB for Elective Open Inguinal Herniorrhaphy
Status:
Completed
Trial end date:
2018-02-17
Target enrollment:
Participant gender:
Summary
Open inguinal herniorrhaphy is a common outpatient surgical procedure. Post-operative pain
can be a significant hindrance to discharge from the post anesthesia care unit. Pain can be
treated with opioid therapy, but the literature supports that these agents are known to
create or exacerbate adverse effects and complications, including post-operative nausea and
vomiting, hypoxia, and urinary retention. In contrast, analgesia provided by regional
anesthesia results in a decreased risk of the aforementioned complications.1 Because of this,
various regional anesthetic techniques have been developed to provide analgesia following
open herniorrhaphy. One technique is a combined ilioinguinal and iliohypogastric nerve block
(IINB), which has been shown to decrease the initial pain after inguinal herniorrhaphy.2 The
quadratus lumborum block (QLB) is a newer regional anesthetic technique that we think could
be as effective as IINB at providing pain control following open herniorrhaphy. Additionally,
because local anesthetic injected during a QLB has the potential to spread cranially into the
thoracic paravertebral space following its lumbar deposition it could lead to alleviation of
both somatic and visceral pain.3 This might therefore improve the quality and or duration of
analgesia as compared to the IINB. To the best of the author's knowledge there has been no
investigation comparing the efficacy, with regards to post-operative pain management, between
IINB and QLB.
Phase:
Phase 2
Details
Lead Sponsor:
Wake Forest University Health Sciences
Treatments:
Anesthetics Anesthetics, Local Bupivacaine Clonidine Epinephrine Epinephryl borate Racepinephrine