Overview

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

Status:
Recruiting
Trial end date:
2031-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which types of breast cancer tumors and by learning more about which early indicators of response (tumor analysis prior to surgery via magnetic resonance imaging (MRI) images along with tissue and blood samples) are predictors of treatment success.
Phase:
Phase 2
Details
Lead Sponsor:
QuantumLeap Healthcare Collaborative
Treatments:
Ado-Trastuzumab Emtansine
Albumin-Bound Paclitaxel
Antibodies, Monoclonal
Carboplatin
Cemiplimab
Doxorubicin
Durvalumab
Irinotecan
Letrozole
Liposomal doxorubicin
Metformin
Olaparib
Paclitaxel
Pembrolizumab
Pertuzumab
Talazoparib
Trastuzumab
Trebananib
Tucatinib
Veliparib