Overview

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

Status:
Recruiting
Trial end date:
2022-11-01
Target enrollment:
Participant gender:
Summary
The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.
Phase:
Phase 2
Details
Lead Sponsor:
QuantumLeap Healthcare Collaborative
Collaborators:
Columbia University
Emory University
Georgetown University
Hoag Memorial Hospital Presbyterian
Kalispell Regional Medical Center
Long Beach Memorial Medical Center
Main Line Health
Montefiore Medical Center
Northwestern University
Sanford Health
University of Alabama at Birmingham
University of California, Davis
University of California, San Diego
University of California, San Francisco
University of Colorado, Denver
University of Iowa
University of Minnesota
University of Pennsylvania
University of Southern California
Wake Forest University Health Sciences
Yale University
Treatments:
Apremilast
Celecoxib
Cyclosporine
Cyclosporins
Famotidine
Icatibant
Remdesivir
TAK-652