The purpose of this study is to determine if the events leading to smoking-associated
centrilobular and paraseptal emphysema are caused by a failure of the lungs' inherent
mechanisms to block hypoxic pulmonary vasoconstriction (HPV) in areas of smoking-induced
inflammation.
Phase:
Phase 4
Details
Lead Sponsor:
Eric A. Hoffman University of Iowa
Collaborators:
National Heart, Lung, and Blood Institute (NHLBI) National Institutes of Health (NIH)