Hypoxia-guided Radiotherapy With Cisplatin-etoposide in Stage I-III : Small Cell Lung Cancer(SCLC)
Status:
Withdrawn
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
Since radiation dose escalation to a large volume of tumour inevitably will induce higher
toxicity than is currently the case, efforts must be made to limit the volume of tissue
irradiated. Moreover, the irradiation of larger tumour volumes leads to a lower achievable
tumour dose when keeping the normal tissue doses constant. Central is thus the question
whether it would be possible to limit the volume of tumour to be boosted by selectively
escalating the radiation dose to specific disease sites which are theoretically more prone to
relapse.