Hypofractionated Stereotactic Radiotherapy for Patients With Recurrent High Grade Glioma

• Status: Active, not recruiting
• Trial end date: 2022-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The study is aimed to evaluate efficacy and safety of re-irradiation for patients with recurrent high grade gliomas after other treatment.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Istituto Clinico Humanitas

Criteria

Inclusion Criteria:

• Age > 18 years

• Karnosky performance status (KPS) ≥70

• Patients aged >70 years with KPS ≥80

• Histopathologically confirmed grade III-IV glioma

• Estimated survival ≥ 3 months

• Any Tumor volume

• Unifocal tumor

• Interval time from previous radiotherapy ≥ 6mesi

• Normal liver, Kidney and bone marrow function

• Written informed consent

Exclusion Criteria:

• KPS < 70

• Multifocal tumor

• Other primary cancer

• Pregnant women