Hypertrophic Scar Prevention by Novel Topical Gel Application
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Researchers are trying to find out more about the side effects of topical (applied to the
skin) Pentamidine, to determine if it is safe for use in people. They also want to find out
if topical use of Pentamidine can help treat hypertrophic scars.
Pentamidine is a medicine that is currently used to treat certain kinds of infection. It is
most often given by intravenous (into a vein) or inhalation (through a breathing device).
This medication is approved by the U.S. Food and Drug Administration (FDA) for use in these
forms.
Everyone in this study will receive topical Pentamidine (TP) in a silicone based gel (PCCA
Pracasil Plus). Topical treatment of Pentamidine is still experimental and has not been
formally tested for safety or effectiveness in a randomized control trial within the United
States. The FDA has allowed the use of topical Pentamidine in this research study.