Overview

Hypertonic Saline to Reduce Hospital Admissions in Bronchiolitis

Status:
Completed
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
Inhaled 3% hypertonic saline (HS) administered every 2-8 hours to infants admitted to hospital with viral bronchiolitis has been shown to improve airway clearance and reduces length of stay. Hypothesis: When infants first present to the ER, frequent administration of HS over a brief time period will provide significant symptom improvement such that the need for hospital admission will be reduced. Objective: To determine in a randomized, controlled and double-blind fashion if the short term intensive use of inhaled 3% hypertonic saline (HS) in the Emergency Room (ER) can reduce the rate of hospital admission for infants presenting with moderately severe viral bronchiolitis.
Phase:
Phase 2
Details
Lead Sponsor:
Queen's University
Collaborators:
Kingston General Hospital
Kingston Health Sciences Centre
Religious Hospitallers of Saint Joseph of the Hotel Dieu of Kingston
Royal Victoria Hospital Of Barrie
Treatments:
Albuterol
Pharmaceutical Solutions