Hypertonic Saline Dextran in Pediatric Cardiac Surgery

• Status: Completed
• Trial end date: 2005-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether infusion of hypertonic saline dextran attenuates the inflammatory response and the water overload, during and after major cardiac surgery in small children.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oslo University Hospital
• Collaborator: BioPhausia
• Treatments: Dextrans; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Patients with congenital heart defect undergoing surgery using cardio pulmonary bypass (CPB).

• Age below 17 weeks

Exclusion Criteria:

• Preoperative: organ failure (other than heart), serum sodium > 155 mmol/l, central venous pressure > 12 mmHg

• Perioperative: core temperature < 25 ºC on CPB, re-heparinization, re-operation