Hypertonic Lactate After Cardiac Arrest

• Status: Not yet recruiting
• Trial end date: 2025-05-15
• Target enrollment: 0
• Participant gender: All

Summary

The study is intended to test the hypothesis that sodium lactate infusion after resuscitation from a cardiac arrest will decrease the magnitude of brain damage, as measured by the serum biomarker concentration of NSE.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Erasme University Hospital

Criteria

Inclusion Criteria:

• Age > 18 years old

• Sustained (> 20 minutes) return of spontaneous circulation (ROSC)

• Comatose (GCS < 9)

• Time to ROSC > 15'

Exclusion Criteria:

• Protected categories (Pregnant women, Prisoners)

• Anticipated withdrawal of support within 24 hours

• Traumatic cause of cardiac arrest

• time from ROSC to inclusion > 1hour

• Inclusion in any other interventional trial