Overview

Hyperinsulinemia in Prediabetes Mediated by Interleukin-1β

Status:
Not yet recruiting
Trial end date:
2024-05-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical study is to test whether postprandial insulin secretion in subjects with prediabetes is mediated by Interleukin-1β and may be influenced by administration of the medicinal product anakinra (Kineret®). The main question it aims to answer is whether there is a difference in insulin secretion following a standardized mixed-meal test under anakinra compared to placebo.
Phase:
Phase 2
Details
Lead Sponsor:
University Hospital, Basel, Switzerland
Treatments:
Interleukin 1 Receptor Antagonist Protein