Hypericum vs Fluoxetine for Mild to Moderate Adolescent Depression
Status:
Terminated
Trial end date:
2010-11-01
Target enrollment:
Participant gender:
Summary
The study is a pilot study where adolescents 12 - 18 years of age with mild to moderate
depression will be randomized to receive either hypericum 250mg twice daily or fluoxetine
10mg daily increased to 20mg daily after 1 week and the option to increase to 40mg daily
after 4 weeks. Patients will be treated for a total of 8 weeks. Efficacy will be measured
using the CDRS-R, BDI-II and the CGI scales. Safety parameters include blood tests,
urinalysis and ECG.