HyperHAES Versus Placebo - Effect on Intracranial Pressure in SAH Patients

• Status: Completed
• Trial end date: 2004-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether 7.2% NaCl in 6% hydroxyethyl starch will lower intracranial pressure (ICP) in SAH-patients with normal or moderately elevated ICP in a placebo controlled study, and to describe the haemodynamic effects.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oslo University Hospital
• Treatments: Hydroxyethyl Starch Derivatives; Pharmaceutical Solutions

Criteria

Inclusion criteria:

• Subarachnoid Hemorrhage, source of bleeding radiologically or surgically secured

• Age > 18 years

• Mechanically ventilated

• Sedated

• Stable hemodynamics

• Stable intracranial pressure between 10 - 20 mmHg

Exclusion criteria:

• Serum sodium > 160 mmol/l