Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients

• Status: Completed
• Trial end date: 2008-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Hydroxyzine is one of antihistamines that antagonizes H1 receptor, and it's effects are reducing pruritus, nausea/vomiting, and the mild effect of sedation.With these effects Hydroxyzine should be used in the prevention of these symptoms.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Hydroxyzine; Morphine

Criteria

Inclusion Criteria:

• ASA classification 1-2

• Age from 18-60 years old

• Body mass index (BMI) below 35

• Accepted combined spinal-general anesthesia

Exclusion Criteria:

• Previous history of Hydroxyzine allergy

• Underlying diseases of urticaria, pruritus, nausea vomiting and motion sickness

• Previous complications of procedure or anesthesia