Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT
Status:
Completed
Trial end date:
2020-05-31
Target enrollment:
Participant gender:
Summary
This will be a pilot, 12-month phase II, open label, randomized, two-arm, single-blinded,
placebo-controlled, parallel clinical trial of individuals undergoing TPAIT (Total
Pancreatectomy and Autologous Islet Transplantation) for treatment of chronic pancreatitis
(CP). The two study arms consist of HCQ-treated (Hydroxychloroquine) and placebo-treated
individuals. The purpose of this study is to investigate the effects of HCQ administration
compared to placebo on islet cell function post-autologous transplantation.
Phase:
Phase 2
Details
Lead Sponsor:
The Cleveland Clinic
Collaborators:
Allegheny Singer Research Institute Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) Stanford University