Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation

• Status: Recruiting
• Trial end date: 2022-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Hydromorphone has a clear analgesic effect, and has few advantages in respiratory depression and gastrointestinal motility. The study will further explore the continuous pumping-dose of hydromorphone for ICU non-mechanical ventilation patients and monitor its effective plasma concentration as well as evaluates the safety and effectiveness of hydromorphone for ICU non-mechanical ventilation patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nanfang Hospital of Southern Medical University
• Treatments: Butorphanol; Fentanyl; Hydromorphone

Criteria

Inclusion Criteria:

• Age ≥18 years old;

• Non-mechanical ventilation patients with expected ICU stay time >24h

• People with moderate to severe pain who need immediate analgesic treatment (NRS ≥ 4 or BPS ≥ 5 points, CPOT ≥ 3);

Exclusion Criteria:

• pregnancy；

• can not get pain score from patients

• allergy to drugs

• ....