Hydrocodone For Pain Control in First Trimester Surgical Abortion

• Status: Completed
• Trial end date: 2011-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether preoperatively administered hydrocodone/acetaminophen (HC/APAP) reduces pain during a first trimester surgical abortion.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Elizabeth Micks
• Collaborator: Planned Parenthood Federation of America
• Treatments: Acetaminophen; Acetaminophen, hydrocodone drug combination; Hydrocodone; Ibuprofen; Lidocaine; Lorazepam; Oxycodone

Criteria

Inclusion Criteria:

• Aged 18 years or older

• Voluntarily requesting surgical pregnancy termination

• Pregnancy with intrauterine gestational sac up to 10 weeks 6 days gestation, dated by ultrasound

• Eligible for suction curettage

• English or Spanish speaking

• Good general health

• Able and willing to give informed consent and agree to terms of the study

Exclusion Criteria:

• Gestational ages 11 weeks or more

• Incomplete abortion

• Premedication with misoprostol

• Use of any opioid medication within the past 7 days

• Use of heroin within the past 7 days

• Requested opioids or IV sedation prior to start of the procedure

• Patients who refuse ibuprofen or lorazepam

• Contraindications or allergies to HC/APAP, lidocaine, ibuprofen, or lorazepam

• Significant medical problem necessitating inpatient procedure

• Adnexal mass or tenderness on pelvic exam consistent with pelvic inflammatory disease

• Known hepatic disease