Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study (0954A-314)

• Status: Completed
• Trial end date: 2006-02-08
• Target enrollment: 0
• Participant gender: All

Summary

An efficacy and safety study of hydrochlorothiazide (+) losartan potassium compared to amlodipine at week 12 in Korean patients with essential hypertension

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Treatments: Amlodipine; Hydrochlorothiazide; Losartan

Criteria

Inclusion Criteria:

• Patients of age 20 70 75 with essential hypertension

• SiDBP 90 ~ 114mmHg at V1 & V2

Exclusion Criteria:

• Patient has known or suspected secondary hypertension

• Patient has a history of malignant hypertension (SiSBP > 210mmHg)

• Individuals has a known sensitivity or intolerance to HCTZ or any AIIAs, or any sulfonamide-derived drugs.

• Patient has shown significant abnormal laboratory evaluations