Hyaluronic Acid Evaluation as Adjuvant to Temporomandibular Joint Arthroscopy

• Status: Completed
• Trial end date: 2019-07-09
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the addition of hyaluronic acid to temporomandibular joint arthroscopy in the treatment of internal derangements in adults. A participants group will receive temporomandibular joint arthroscopy plus hyaluronic acid, while the other group will receive temporomandibular joint arthroscopy. Hypothesis: hyaluronic acid as an adjunct in temporomandibular joint arthroscopic surgery provides additional benefits in clinical and radiological outcomes in temporomandibular joint internal derangements.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidad Complutense de Madrid
• Collaborators: Fundación de Investigación Biomédica - Hospital Universitario de La Princesa; Zambon SpA
• Treatments: Amoxicillin; Analgesics; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Clavulanic Acid; Clavulanic Acids; Dexamethasone; Diclofenac; Hyaluronic Acid

Criteria

Inclusion Criteria:

• Diagnosis of temporomandibular joint internal derangements in Wilkes stages III and IV by magnetic resonance imaging

• Limitation of maximum oral opening or duplication of joint pain by palpation

• lack of response to conservative therapies

Exclusion Criteria:

• Any degenerative systemic disease of muscular or joint involvement (rheumatoid arthritis, etc.)

• Previous temporomandibular joint surgical treatment: arthrocentesis, arthroscopy or open surgery

• Infection in Temporomandibular Joint or in puncture site

• Hyaluronic acid or corticosteroids injection in Temporomandibular Joint in previous 6 months

• Pregnant or breastfeeding women

• Participants who refuse to complete the treatment or unavailable to complete the follow-up