Overview
Human Chorionic Gonadotropin Stimulation Effects on Steroidogenesis in Men With Klinefelter Syndrome
Status:
Completed
Completed
Trial end date:
2014-07-01
2014-07-01
Target enrollment:
0
0
Participant gender:
Male
Male
Summary
The study design included six visits. During the first visit (visit 0), the subjects underwent physical examination(height, weight, body mass index (BMI), arm span, and upper segment measurement) and testicular ultrasound (US) for the calculation of testicular volume. At 0800 h of day 0, all subjects provided a basal blood sample immediately followed by a single intramuscular injection of hCG of 5000 IU. Further five visits were performed each of five following consecutive days after the hCG injection. A blood sample was taken at each visit after an overnight fastPhase:
N/AAccepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Azienda USL ModenaTreatments:
Chorionic Gonadotropin
Criteria
Inclusion Criteria:- Klinefelter syndrome diagnosis at kariotype evaluation for the study group
- Healthy age-matched men in the control group
Exclusion Criteria:
- previous or ongoing androgen therapy