Overview

Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function

Status:
Completed

Trial end date:
2013-05-01

Target enrollment:

Participant gender:

Summary

The following are done for screening procedures to determine if patients are eligible for this study: blood count, kidney and liver blood tests. Patients will complete a 6-minute walk test. Patients will be instructed to follow a no-added-salt diet for 1-3 weeks before the study and for the whole duration of the study. Diet instructions will be given to the patient and the patient will collect his/her urine for 24 hours before the active study day. Patients will need to avoid strenuous exercise and abstain from smoking, alcohol, and caffeine for 3 days prior to the study days. Patients will remain on their regular medications.

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

Mayo Clinic

Collaborators:

National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)

Treatments:

Natriuretic Peptide, Brain