Overview

Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)

Status:
RECRUITING
Trial end date:
2027-06-30
Target enrollment:
Participant gender:
Summary
Hepatic encephalopathy (HE), a severe complication of decompensated cirrhosis, is characterized as neurocognitive dysfunction. Emerging evidence suggests the potential role of human albumin infusion for the treatment of HE, but its optimal dosage remains undefined. Therefore, the investigators planned a randomized controlled trial (RCT) to compare the efficacy of human albumin infusion at different dosages in in patients with liver cirrhosis and overt HE.
Phase:
NA
Details
Lead Sponsor:
General Hospital of Shenyang Military Region
Treatments:
Albumins
Amino Acids, Branched-Chain
Arginine
Lactulose
ornithylaspartate
Rifaximin