How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Patients with chronic kidney disease and end stage renal disease have greater cardiovascular
risk than the general population. Vitamin D analogues have been shown in observational
studies to have mortality benefit for these patients. This study is designed to investigate
doxercalciferol's effect on the vasculature (i.e. endothelial cell function) as a possible
mechanism to explain the mortality benefit.