How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

• Status: Withdrawn
• Trial end date: 2015-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the effect of intraoperative lidocaine infusion on postoperative orientation and concentration in elderly patients having general anesthesia for orthopedic surgeries requiring a minimum 2 days hospitalization.

This study will also aim to determine whether intraoperative lidocaine infusion during general anesthesia improves recovery and patient outcome, as well as to determine whether lidocaine infusion decreases postoperative opioid (pain medication) usage.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cedars-Sinai Medical Center
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Scheduled to undergo orthopedic surgery under general anesthesia requiring a minimum two-day hospitalization (e.g. THA, TKA, hardware removal)

• 65 years of age or older

• ASA Physical Classification I - IV

• Willingness and ability to sign an informed consent document

• English-speaking

Exclusion Criteria:

• Inability to consent or complete cognitive assessments

• Inability to use a PCA system

• Allergy to lidocaine or any other medication administered as part of this protocol

• Emergency surgery