Overview

Houston Emergency Opioid Engagement System

Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
0
Participant gender:
All
Summary
The Houston Emergency Response Opioid Engagement System (HEROES) is a community-based research program integrating assertive outreach, medication-assisted treatment, behavioral counseling, peer recovery support, and paramedic follow-up in Houston Texas. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston
Treatments:
Buprenorphine, Naloxone Drug Combination
Criteria
Inclusion Criteria:

- In otherwise good health based on physician assessment and medical history

- Tests positive in urine sample for opioids

- Patients express a willingness to stop opioid use

- Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR)
criteria for opioid dependence

- Patients must be able to speak English

- Be agreeable to and capable of signing informed consent

Exclusion Criteria:

- Non-English-speaking patients

- Have a known sensitivity to buprenorphine or naloxone

- Be physiologically dependent on alcohol, benzodiazepines or other drugs of abuse that
require immediate medical attention. Other substance use diagnoses are not
exclusionary.

- Have a medical condition that would, in the opinion of the study physician, make
participation medically hazardous, including unstable cardiovascular disease,
neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)

- Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an
immediate suicide risk

- Be a nursing or pregnant female