Overview

Household-level Impact of IPT of Malaria in Schoolchildren

Status:
Recruiting
Trial end date:
2021-06-30
Target enrollment:
Participant gender:
Summary
The study will evaluate the household-level impact of IPT for malaria in schoolchildren on malaria transmission, using a randomized trial design. Two schools in Busia district will be randomly selected and randomize to either IPT with dihydroartemisinin piperaquine (DP, IPT arm), or standard of care (no intervention). A single dose/round of IPT with DP (40mg/320mg tabs, Fosun Pharmaceuticals) will be given to the children in the intervention arm. The full dose will be given as oral tablets once a day for 3 consecutive days to all eligible children in the intervention school. Surveys will be conducted in households of 100 randomly selected children in each of the study arms at baseline, one month and three months following the intervention. The target population will include all household members of the selected households.
Phase:
Phase 3
Details
Lead Sponsor:
Makerere University
Treatments:
Artenimol
Dihydroartemisinin
Piperaquine