Overview

Hormones Inflammation and Thrombosis

Status:
Terminated
Trial end date:
2013-11-01
Target enrollment:
0
Participant gender:
Female
Summary
The investigators are attempting to determine if the response to aspirin in women is related to the level of estrogen and progesterone that a woman has.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Johns Hopkins University
Treatments:
Aspirin
Hormones
Criteria
Inclusion Criteria:

1. Women age 18-80

2. Signed informed consent.

Exclusion Criteria:

1. History of CAD, Cerebrovascular Accident (CVA) or Peripheral Artery Disease (PAD),

2. On chronic aspirin therapy,

3. On chronic NSAID therapy.

4. Chronic anticoagulation with coumadin,

5. Known thrombocytopenia (Platelet count < 100,000),

6. Pregnancy (self-report),

7. Currently on any type of contraceptive or hormone replacement therapy,

8. Hysterectomy and/or oophorectomy.

9. Recent GI bleeding

10. Bleeding diathesis

11. Chronic Systemic Infection