Overview

Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia

Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Hormone therapy may stop the growth of cancer cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy may kill more cancer cells. It is not yet known which hormone therapy and chemotherapy regimen is most effective for acute lymphoblastic leukemia. PURPOSE: Randomized phase III trial to compare the effectiveness of different steroid therapy and chemotherapy regimens in treating children who have acute lymphoblastic leukemia.
Phase:
Phase 3
Details
Lead Sponsor:
Medical Research Council
Treatments:
6-Mercaptopurine
Asparaginase
Cyclophosphamide
Cytarabine
Daunorubicin
Dexamethasone
Doxorubicin
Liposomal doxorubicin
Mercaptopurine
Methotrexate
Pegaspargase
Prednisolone
Thioguanine
Vincristine