Hormone Replacement for Premature Ovarian Insufficiency
Status:
Withdrawn
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The investigators intend to establish feasibility/acceptability of a pilot randomized trial
comparing hormone replacement therapy (HRT) and combined oral contraceptives (COCs) in women
with premature ovarian insufficiency to estimate differences in quality of life (QOL) and
serum hormone assays and markers of bone turnover/cardiovascular risk. At baseline, QOL
survey will be administered and serum testing performed. Patients then randomized to HRT or
COCs. Repeat testing will be performed after 3 and 6 months.