Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find out if the anti-HIV drugs nelfinavir (NFV),
lopinavir/ritonavir (LPV/r), and efavirenz (EFV) change the amount of estrogen in the blood
when taken along with hormone replacement therapy (HRT) for menopause.
HRT can be helpful for treating bothersome symptoms of menopause. However, it is not
routinely used in HIV-infected postmenopausal women because it is not known how HRT interacts
with anti-HIV drugs. The information obtained from this study will help doctors make
recommendations for HRT in postmenopausal HIV-infected women.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)