Overview

Hormonal Contraceptive Methods on Immunologic Changes in the Female Genital Tract (FGT) and Systemically

Status:
Recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
The study is a prospective cohort study to explore the mechanisms underlying the HIV risk associated with pharmacologic doses of exogenous sex hormones via hormonal contraceptives specially progestin-containing hormonal contraception (HC). The study seeks to test that HC induce immunologic changes capable of altering HIV susceptibilities, that these effects will vary by contraceptive type, and that they will be modified by the vaginal microenvironment.
Details
Lead Sponsor:
Emory University
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institutes of Health (NIH)
Treatments:
Contraceptive Agents
Copper
Desogestrel
Etonogestrel
Levonorgestrel
Medroxyprogesterone
Medroxyprogesterone Acetate