Histamine H1/H2 Receptors and Training Adaptations

• Status: Completed
• Trial end date: 2021-04-14
• Target enrollment: 0
• Participant gender: Male

Summary

Exercise training is beneficial for both health and performance. Histamine has been shown to be involved in the acute exercise response. The current study addresses the role of histamine H1/H2 receptor signaling in the chronic training-induced adaptations. Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wim Derave
• Collaborators: Research Foundation Flanders; University of Copenhagen
• Treatments: Famotidine; Fexofenadine

Criteria

Inclusion Criteria:

• Sedentary or low levels of physical activity

• Caucasian

Exclusion Criteria:

• Chronic diseases

• Medication use

• Smoking

• Excessive alcohol consumption

• Seasonal allergies