Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile
Status:
Completed
Trial end date:
2021-10-20
Target enrollment:
Participant gender:
Summary
Botulinum type A (BTX-A) is an easy and efficacious treatment for gingival smile (GS).
However, the necessary for higher-doses among patients are controversial. The objective was
to compare the reduction of gingival exposure using two methods in patients with different
dosage. In this prospective self-controlled study, healthy GS participates who had an
anterior gingival exposure (GE) of more than 3 mm were enrolled and administered with 2-5 U
BTX-A (total, 4-10 U) injections into 1-2 points according to the severity presented
pretreatment in the Average-dose Method. And after 8 months, the Higher-doses Method was
administered the same point injection of 3-10 U BTX-A (total, 6-20 U). Data were collected at
baseline and 4, 12, 32 and 60 weeks of follow-up.