High Volume Simethicone VCE Clinical Trial

• Status: Completed
• Trial end date: 2019-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Video capsule endoscopy (VCE) is a procedure where a small camera is swallowed to examine the small bowel. Although the procedure is useful for diagnosing small bowel diseases, air bubbles can obscure the recorded images. Simethicone is a medication that can be used to disperse the air bubbles. However, prior studies using this medication have shown only a modest benefit. In our study, we would like to investigate whether increasing the amount of medication will improve the recorded images further.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Simethicone

Criteria

Inclusion Criteria

1. Patients undergoing small bowel video capsule endoscopy

Exclusion Criteria

1. Patients with a contraindication to VCE (small bowel strictures, oropharyngeal dysphagia, pregnancy, patients who are not surgical candidates)

2. Endoscopic insertion of video capsule endoscope

3. Inpatient procedures for active GI bleeding

4. Patients with fluid restriction or who are unable to drink up to 900 ml of fluid within 10 minutes prior to the VCE