High Volume Caudal Study

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

The primary objective is to evaluate the effect of clonidine on the duration of analgesia provided by a high volume-low concentration caudal block for pediatric aurgical procedres. In addition, caudal clonidine's effect on length of recovery and post-operative emergence agitation will be measured.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Medical University of South Carolina
• Treatments: Clonidine; Epinephrine; Epinephryl borate; Racepinephrine; Ropivacaine

Criteria

Inclusion Criteria:

• 3 years old or less

• Weight <= 13.3kg

• American Society of Anesthesiology Physical Status (ASA) 1 or 2

• Undergoing circumcision surgery

• Patients whose plan of care includes caudal block

Exclusion Criteria:

• Known allergy to clonidine, epinephrine, or amide local anesthetics

• Inability or unwillingness of parent or legal guardian to give informed consent