High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery

• Status: Recruiting
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a feasibility study to determine if enough patients undergoing elective or urgent cardiac surgery, can be enrolled in a study where patients are randomized to receive high spinal anesthesia as an adjunct to general anesthesia for their cardiac surgery. The primary clinical outcome will be the incidence of post-operative delirium.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Manitoba
• Treatments: Bupivacaine; Morphine

Criteria

Inclusion Criteria:

• Adult (>18 years old) patients

• Undergoing elective or urgent cardiac surgical procedures with cardiopulmonary bypass

Exclusion Criteria:

• Contraindications to spinal anesthesia such as active anticoagulation, clopidogrel within 7 days of surgery, ticagrelor within 3 days of surgery and all other contraindications to lumbar puncture

• Pre-existing psychiatric diagnoses such as schizophrenia or manic-depressive disorder

• Complex aortic surgery (> hemi-arch repair, descending thoracic surgery)

• Difficult airway requiring an awake intubation

• BMI > 50