High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy of the combination of surgery, conventional chemotherapy, sequential high-dose chemotherapy with peripheral blood stem cell transplantation and reduced dose radiation therapy in high-risk PNET brain tumors.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Gustave Roussy, Cancer Campus, Grand Paris
• Treatments: Carboplatin; Etoposide; Melphalan; Thiotepa

Criteria

Inclusion Criteria:

• Medulloblastoma in patients less than 5 years of age

• Brain PNET in patients less than 10 years of age

• Histologically documented diagnosis

• Body weight of > 8 kg

Exclusion Criteria:

• Parents' refusal