High-Resolution Assessment of Extracranial Plaques in Evolocumab Treatment
Status:
Not yet recruiting
Trial end date:
2024-10-01
Target enrollment:
Participant gender:
Summary
This study intends to explore the therapeutic effect of PCSK9i Evolocumab on atherosclerotic
plaques in cerebral arteries (including carotid and vertebral arteries) compared with
intensive statin treatment, and monitor the pathological properties of carotid/vertebral
artery plaques with OCT technology. At the same time, three-dimensional ultrasound and
high-resolution magnetic resonance are used to explore the new mechanism of pathological
changes of cerebral atherosclerotic plaques in a multidimensional manner.